Quantitative tools are an essential element of scientific enquiry, yet many students lack the confidence to use these tools in practice. The Quantitative Skills panels are designed to remove this ‘fear factor’, explaining in a clear, straightforward way a number of quantitative topics that help us understand genetics.

Prologue: Five Great Ideas

Chapter 1: Evolution, Genomes and Genetics

Chapter 2: The Central Dogma of Molecular Biology

Chapter 3: Genome Organization, Structure, and Variation

Chapter 4: Descent with Modification: DNA Replication and Mutation

Quantitative Skills: The Luria-Delbruck Fluctuation Test

Chapter 5:  Basic Principles of Single Gene Inheritance

Quantitative Skills: The chi-square Test

Chapter 6: The Cellular Basis for Mendelian Genetics: Mitosis and Meiosis

Chapter 7: X-linked Genes and Sex Chromosomes

Chapter 8: The Inheritance of Multiple Genes

Chapter 9: The Location of Genes on Chromosomes: Linkage and Genetic Maps

Quantitative Skills: Three-factor Crosses

Chapter 10: Human Genetic Mapping, GWA Studies and Complex Traits

Quantitative Skills: Heritability

Chapter 11: Exchange and Evolution

Chapter 12: Transcription: Reading and Expressing Genes

Chapter 13: Translation: From Nucleic Acids to Amino Acids

Chapter 14: Networks of Gene Regulation

Quantitative Skills: Bacterial growth curves: a quantitative perspective

Chapter 15: Genetic Analysis of Cellular Processes

Quantitative Skills: Estimating the Number of Genes: Saturation in Genetic Screens

Chapter 16: The Genetics of Populations

Quantitative Skills: Quantitative concepts in population genetics

Chapter 17: Metagenomics: Genomes of Communities