2911, 2016

Tracking Migration with Mitochondrial and Y-chromosome DNA

By |November 29th, 2016|A Human Angle|

Wherever we go, we bring along traces of where we have been.  In genetic and genomic terms, this is the process of migration, the leaving of one population and the joining of another, either because […]

2908, 2016

How Toadstools Affect Transcription

By |August 29th, 2016|A Human Angle|

One of the most common and widespread mushrooms in Europe is also among the most toxic toadstools.  Amanita phalloides (familiarly known as the death cap mushroom or toadstool) grows throughout European forests, typically at the […]

1107, 2016

Exome Sequencing and Direct Searches for Causative Mutations

By |July 11th, 2016|A Human Angle|

Genome-wide association studies (GWAS) currently dominate the research literature in human genetics, but they have some limitations.  Foremost among these is that, while a GWAS identifies regions of the genome associated with a trait or […]

405, 2016

ABO Blood Types

By |May 4th, 2016|A Human Angle|

Among genetic traits that we all share, the most familiar single gene trait in humans is probably our ABO blood type.  Other familiar shared heritable human traits, such eye color, are not controlled by a […]

604, 2016

Red-Green Colorblindness

By |April 6th, 2016|A Human Angle|

Mutations that arise spontaneously usually occur as a result of unrepaired errors during replication, as discussed in Chapter 4, or as transposable element movement, as discussed in Chapter 3.  However, a few mutant alleles arise […]

903, 2016

Analyzing the Black Death by Phylogenetics

By |March 9th, 2016|A Human Angle|

Yersina pestis is a bacterial species that causes a deadly disease known as the Plague. Currently, outbreaks of the Plague occur in very few parts of the world, but ancient outbreaks had a major role […]