Our current understanding of genetics has been shaped by experimentation, enquiry, and the refinement of ideas over the course of several hundred years. The An Historical Perspective panels reveal some of the historical events that have influenced genetics as we know it today.

Prologue: Five Great Ideas

Chapter 1: Evolution, Genomes and Genetics

Chapter 2: The Central Dogma of Molecular Biology

Chapter 3: Genome Organization, Structure, and Variation

Chapter 4: Descent with Modification: DNA Replication and Mutation

An Historical Perspective: The Meselson-Stahl Experiment and Semi-Conservative Replication

Chapter 5:  Basic Principles of Single Gene Inheritance

An Historical Perspective: Did Mendel Cheat?

Chapter 6: The Cellular Basis for Mendelian Genetics: Mitosis and Meiosis

Chapter 7: X-linked Genes and Sex Chromosomes

Chapter 8: The Inheritance of Multiple Genes

Chapter 9: The Location of Genes on Chromosomes: Linkage and Genetic Maps

An Historical Perspective: Why Didn’t Mendel Encounter Linkage?

Chapter 10: Human Genetic Mapping, GWA Studies and Complex Traits

Chapter 11: Exchange and Evolution

Chapter 12: Transcription: Reading and Expressing Genes

Chapter 13: Translation: From Nucleic Acids to Amino Acids

Chapter 14: Networks of Gene Regulation

Chapter 15: Genetic Analysis of Cellular Processes

An Historical Perspective: Archibald Garrod and Inborn Errors of Metabolism

Chapter 16: The Genetics of Populations

Chapter 17: Metagenomics: Genomes of Communities